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June 2022 -
Volume 20, Issue 6


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From the Editor

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The prevalence and outcome of Stenotrophomonas maltophilia bacteraemia over a 5 year period at tertiary care in Saudi Arabia
Ali Amer Al Shehri, Bader Ibrahim Asiri, Khalid Mousa Asiri, Mohammad Abdullah Albakkar, Salmah Muidh Ali Alharbi, Saeed Saad Alqahtani, Sultan Ahmad Alkahtani, Yahya Mohammed Aloosh
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022. 9525054

Regional Covid

Acceptance, perception and awareness regarding COVID-19 vaccination among general population in Karachi, Pakistan
Tafazzul Hyder Zaidi, Nadira Hyder Zaidi, Aamer Humayun Ansari, Sobia Memon, Faheem Ahmed, Aleena Waheed, Javeria Abdul Mateen, Amtul Bari, Fatima Tuz Zehra
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022. 9525052

Misconceptions and Fears among Primary Health Care Physicians in Aseer Region, Saudi Arabia, regarding COVID-19
Ameen Mohammed Hashem Malky, Khalid M. Almosa
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022. 9525066

Review

Granulomatous Gastritis in Crohn's Disease - is it Common or Rare: Review Article
Al Amri Turki Abdullah, Parul Tandon
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022. 9525060

Diabetic Ketoacidosis: A Review Article
Hani Raka Karrar, Mahmoud Ismail Nouh, Rehab Salah Aldin Alhendi,
Osama Habib Alsaedi, Amal Hassan Abu Sadah, Nouf Mousa Bahri, Mohammed Ghumays M Alharthi, Omar Aziz Bahlol Aldhafeeri,
Salihah Ali Razqan, Mohammed Yahya Mojammam, Hessa Meteq Albalawi, Mohammed Aljunaid Alamin Alsheikh, Naif Ibrahim Saeed Abusharhah,
Saleh Jabbar Alzahrani, Sara Gafar Ali Seedahmed
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022. 9525062

Magnetic resonance cholangiopancreatography in the evaluation of pancreatic and biliary disorders
Shaza Youssef, Thamin Alassaad
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022. 9525073

Classification and Diagnosis of Acute Pancreatitis
Thamin Alassaad, Shaza Youssef
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022. 9525074

Population and Community Studies

Knowledge, Attitude, and Practice towards Over-the-Counter Drugs (OTC) use among adult population in Jeddah, Saudi Arabia

Fathi El-Gamal, Badr Atia Alsahafi, Ibrahim Alsammak, Emad Darwesh, Raad Albogami, Abdullah Taha
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022. 9525056

A Prospective Study Comparing Laparoscopic with Open Appendectomy in Children with Complicated Appendicitis
Younes, Alaa E.
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022. 9525063

Physical Activity and Eating Habits Impact on Attentiveness and Academic Achievement Among Health Specialty Students in University of Hail
Khalid Farhan Alshammari, Abdulmohsin Homoud Almalaq, Fadi Sulaiman Alqassim, Khalid Falah Alqahtani
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022. 9525064

Assessment of Knowledge and practice of Maturity Onset Diabetes of the Young (MODY) among Primary care physicians in Najran, Saudi Arabia
Mohammed Ayed Huneif
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022. 9525065

Primary Healthcare Physicians' Knowledge, Attitude and Practices about Diabetic Foot Prevention and Management in Aseer Region, Saudi Arabia
Hassan Mohammed H. Alqarni, Abdulrahman Mohammed Alshehri,
Shahad Hassan Ali Alhayaza, Ali Al-Mousa
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022. 9525079

Knowledge and awareness level about radial head subluxation mechanism among Saudi population living in western region of Saudi Arabia
Enaam M.Junainah, Areej A. Alsufyani, Abdulaziz B. Alghuraibi, Ahmed F.Aljuhani, Raghad M. Alsaqqa, Huda A. Alzahrani
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022. 9525082

Clinical Review

Allergy to Salbutamol
Turki Alahmadi
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022. 9525086

Middle East Quality Improvement Program
(MEQUIP QI&CPD)


Chief Editor -
Abdulrazak Abyad MD, MPH, MBA, AGSF, AFCHSE

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Publisher -
Lesley Pocock
medi+WORLD International
AUSTRALIA
Email
: lesleypocock@mediworld.com.au
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June 2022 - Volume 20, Issue 6

Granulomatous Gastritis in Crohn’s Disease - is it Common or Rare: Review Article

Corresponding author:
Al Amri Turki Abdullah
Division of Gastroenterology, Department of Internal Medicine,
King Fahad University Hospital, Imam Abdulrahman Bin Faisal University,
Dammam 31441,
Saudi Arabia
Email: taalamri@iau.edu.sa

Received: April 2022 Accepted: May 2022; Published: June 1, 2022. Citation: Al Amri Turki Abdullah, Parul Tandon. Granulomatous Gastritis in Crohn’s Disease - is it Common or Rare: Review Article. World Family Medicine. 2022; 20(6): 54-65. DOI: 10.5742/MEWFM.2022.9525060

Abstract

Background: Granulomas in gastric biopsy specimens are extremely rare; more than half are associated with Crohn’s disease.

In Crohn’s disease, clinical involvement is rare; microscopic disease is more common. Gastric granulomas are found in 9-15%, and a high proportion of Crohn’s patients show upper GI involvement, usually antral. Focal acute inflammation in a background of non-inflamed H. pylori negative mucosa is suggestive of Crohn’s disease and active inflammation in 56% (some inflammatory changes in up to 70%), but only 10% are H. pylori positive.

Objective: The aim of the study was to highlight granulomatous gastritis in Crohn’s disease.

Conclusion: The incidence of gastric Crohn’s is 10% of the cases. The histological diagnosis of Crohn’s disease on gastric samples is suggested by the presence of 1) a focal distribution; 2) chronic active inflammatory lesions; 3) the absence of the Helicobacter Pylori (HP) organism; and 4) granuloma. Focal stromal abnormalities could be a new diagnostic morphologic pattern in gastric Crohn’s disease, sharing the same value as focal cryptal architectural abnormalities in intestinal involvement. Since the majority of patients with Crohn’s disease lack significant symptoms, the true incidence of the disease depends on whether such pictures are sought for and identified.

Keywords: Granulomatous Gastritis,
Crohn’s disease, Chronic inflammatory condition







 


 

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